Independent list · re-checked September 28, 2026 · published by Primortul LLC

Antidote 71

Antidote 71 is an advertising and marketing agency at 600 4th Street in Sioux City with a second office in Omaha. Its work covers branding, video, SEO, SEM, paid social, retargeting, geofencing, email and marketing automation, organised into attract, engage, convert and grow stages. It works mainly with medical, financial, construction and manufacturing companies. Nobody pays to be ranked.

Why it’s hereA full-service Siouxland agency combining branding, video and paid media for regional advertisers, listed by Expertise.com. Number 13 of the advertising agencies in Iowa.

Who leads itRich Mackey, President.

Estimated cost

Estimated: $10,000–$40,000, typical for Iowa advertising retainers; not a quote.

Typical industry estimate, not a quote from any firm on this list.

A fit forMedical, financial, construction and manufacturing companies that want one outside team to run websites, paid media, marketing automation and lead scoring.

Based in
Sioux City, IA
Team size
1–10 people
Led by
Rich Mackey, President
Known for
branding · video · paid social and search · geofencing and retargeting · healthcare and financial services
Best for
Medical, financial, construction and manufacturing companies that want one outside team to run websites, paid media, marketing automation and lead scoring.
Estimated cost

Estimated: $10,000–$40,000, typical for Iowa advertising retainers; not a quote.

Typical industry estimate, not a quote from any firm on this list.

Antidote 71 homepage, captured September 28, 2026
antidote71.com · homepage on September 28, 2026

UpdateFormerly JD Gordon Creative Labs; the team now works remotely across Iowa, Nebraska, North Carolina and Australia.

Sources antidote71.com, expertise.com · LinkedIn ↗

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